Table 3 Parameters used in Fig. 3.

From: First-passage times and normal tissue complication probabilities in the limit of large populations

Parameter

Definition

Fig. 3(a,b)

Fig. 3(c,d)

b

mitosis rate (day−1)

0.0821

0.246

d1

normal cell death rate (day−1)

0.0164

0.0164

d1

irradiated cell death rate (day−1)

0.0164

0.0164

M

population size

1000

1000

\(\ell =\frac{L}{M}\)

critical fraction of population

0.39

0.39

α

LQ model parameter (Gy−1)

0.109

0.109

β

LQ model parameter (Gy−2)

0.0364

0.0364

γ

rate of DNA repair (day−1)

23.7

23.7

R0

initial dose rate of implant (Gday−1)

1.68

1.68

λ

decay rate (day−1)

0.0117

0.0117

  1. Similar parameters were previously proposed in Hanin and Zaider5. We have explicitly included normal-cell birth and death and made the assumption that d1 = d2.