Table 1 In-silico datasets and included resistance-mediating mutations.

From: Detection of low-frequency resistance-mediating SNPs in next-generation sequencing data of Mycobacterium tuberculosis complex strains with binoSNP

Dataset

Mutation

MDR1

rpoB His445Asn

 

katG Ser315Asn

MDR2

rpoB His445Arg

 

katG Trp300Cys

MDR3

rpoB Ser450Leu

 

fabG1 -8 T/A

XDR1

rpoB His445Asn

 

katG Ser315Asn

 

rrs 1401 A/G

 

gyrA Asp94Asn

XDR2

rpoB His445Arg

 

katG Trp300Cys

 

rrs 1401 A/G

 

gyrA Asp94Ala

XDR3

rpoB Ser450Leu

 

fabG1 -8 T/A

 

rrs 1484 G/T

 

gyrB Thr500Asn

PZA1

pncA Val163Ala

PZA2

pncA His82Asp

EMB1

embB Met306Leu

EMB2

embB Gly406Ser

EMB3

embB Gly406Ala

SM1

rpsL Lys43Arg

SM2

rpsL Lys88Arg

RMP1

rpoB Asp435Val

RMP2

rpoB Ile491Phe

INH1

katG Ser315Gly

INH2

fabG1 -15 C/T

FQ1

gyrB Asp461Asn

FQ2

gyrB Glu501Asp

FQ3

gyrA Ser91Pro

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