Figure 2

Comparison of gene expression profiles between each treatment and the control. Volcano plots showing RNA-Seq data from each treatment [(A) C12AHL, (B) fluconazole and (C) C12AHL + fluconazole] relative to the control. The dashed lines represent the cut-off values for p-value (=10⁻⁶) and log₂ fold change (=2) to identify significantly different gene expression. The plots are coloured so that non-significant differentially expressed genes are represented in grey, those with log₂ fold change >2 are shown in green, genes with p-value < 10⁻⁶ are coloured in blue, and those with both log₂ fold change >2 and p-value < 10⁻⁶ are shown in red. Genes that represent proteins involved in the ergosterol biosynthesis pathway have been labelled in the plots.