Table 1 Gene expression data; The C. albicans genes that were significantly affected by both fluconazole only and C12AHL only exposure compared to untreated controls [(Fluconazole vs Control) vs (C12AHL vs Control)]. Genes highlighted in blue are known to be associated with antifungal sensitivity/resistance. (http://www.candidagenome.org/).

CSH1

Aldo-keto reductase

3.36

5.11E-23

1.87

5.61E-07

C3_03460C_A

Protein of unknown function

3.35

5.16E-23

3.19

4.58E-20

C1_01510W_A

Protein of unknown function

2.78

1.81E-16

2.46

2.65E-12

C1_04010C_A IFD1/IFD6 alias

Protein with a NADP-dependent oxidoreductase domain

2.67

1.06E-19

1.68

1.47E-07

LPG20

Aldo-keto reductase family protein

2.44

4.3E-13

1.65

8.38E-06

CRH11

GPI-anchored cell wall transglycosylase

2.30

7.62E-08

−2.36

1.36E-07

WOR4

Predicted C2H2 zinc finger protein

2.09

7.17E-12

2.40

1.18E-14

NRG1

Transcription factor/repressor

1.86

1.93E-12

2.18

4.02E-16

IFD6

Aldo-keto reductase

1.75

6.62E-08

3.02

1.11E-21

SRR1

Two-component system response regulator

1.62

1.27E-06

2.24

1.98E-11

C2_01750C_A

Protein with a life-span regulatory factor domain

1.33

8.99E-07

1.51

4.57E-08

RGS2

Protein of RGS superfamily

1.29

1.1E-07

1.39

3.28E-08

BCR1

Transcription factor

1.26

3.25E-07

1.21

3.28E-06

CR_10230W_A

Histone acetyltransferase activity

0.85

3.82E-06

1.36

2.94E-14

CDR4

Putative ABC transporter superfamily

−1.43

2.18E-08

1.70

6.09E-11

PHHB

Putative 4a-hydroxytetrahydrobiopterin dehydratase

−1.62

5.69E-07

−1.72

2.87E-07

IFR2

Zinc-binding dehydrogenase

−1.79

2.02E-08

−1.78

8.07E-08

RME1

Zinc finger protein

−1.95

4.98E-07

2.17

3.28E-08

ATX1

Putative cytosolic copper metallochaperone

−2.22

8.01E-10

2.75

2.42E-14