Figure 5 | Scientific Reports

Figure 5

From: Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover

Figure 5

PKO mice exhibit decreased DMB-associated mitochondrial biogenesis gene expression. Age-matched wild-type and PKO mice underwent permanent coronary artery ligation and were given vehicle (50 µL DMSO) or DMB (10 pmoles/25 g) i.p. 2 hours after surgery and again 2 days later. Mice were sacrificed 3 days after PCAL (n = 3–7 mice/group) for gene expression analysis. All values are presented as mean ± standard deviation. ANOVA with Tukey posthoc test was used to compare the groups. Gene expression was normalized to the average expression of 18 S and Rpl4.

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