Figure 1 | Scientific Reports

Figure 1

From: Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity

Figure 1

Cell types identified in healthy pediatric and adult bone marrow mononuclear cells (BMMCs) using single cell RNA-seq. (A) UMAP representation of healthy BMMCs from three pediatric (PBMMC; n = 6,836 cells) and two adult (ABMMC; n = 3,467 cells) donors. (B) Expression of cell surface marker genes used to assign cell types: CD79A (B cells), CST3 (monocytes), CD3D (T cells) and HBA1 (erythrocytes). (C) Cell types identified in healthy pediatric and adult BMMCs. (D) Proportion of cells of a given cell type in pediatric and adult BMMCs. (E) Proportion of healthy cells in predicted cell cycle phases per cell type (G1, S and G2/M).

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