Figure 1

The core-pan genome curve of studied S. Typhi genomes. (a) Total number of gene families (pan-genome) and shared gene families (core genome) are plotted for a given number of genomes added sequentially. Total gene families are indicated as mustard dashed line while pink dashed line denotes core gene families. (b) The mustard dashed line indicates the least-square fit to the power law function f(x) = a.x^b where a = 3840.29, b = 0.0852733. The pink dashed line is the least-squares fit to the exponential decay function f1(x) = c.e^(d.x) where c = 4379.51, d = −0.000429421. (c) Pan- and core-genome curve of S. Typhi strains disclosed a minor increase in the size of the pan-genome while the core genome appears to almost close.