Figure 2

COG functional distribution of pan-genome. The histogram illustrates the predicted functionality of proteins assigned to core (orange), accessory (yellow) and unique (green) genes. The COG families were broadly grouped into four category namely information storage and processing (assigned to the L, K, and J categories), cellular processes and signalling (assigned to the V, U, T, O, N, M and D categories), metabolism (assigned to the P, Q, I, H, F, E, G, and C categories), and poorly characterized (assigned to the S, and R categories). COG categories: [C] Energy production & conversion; [D] Cell cycle control, cell division, chromosome partitioning; [E] Amino acid transport & metabolism; [F] Nucleotide transport; [G] Carbohydrate transport & metabolism; & metabolism; [H] Coenzyme transport & metabolism; [I] Lipid transport & metabolism; [J] Translation, ribosomal structure & biogenesis; [K] Transcription; [L] Replication, recombination & repair; [M] Cell wall/membrane/envelope biogenesis; [N] Cell motility; [O] Post-translational modification, protein turnover & chaperones; [P] Inorganic ion transport & metabolism; [Q] Secondary metabolites biosynthesis, transport & catabolism; [R] General function prediction only; [S] Function unknown; [T] Signal transduction mechanisms; [U] Intracellular trafficking, secretion & vesicular transport; [V] Defense mechanisms.