Table 1 General characteristics of ARDKO animal model.

From: Chronic Sympathetic Hyperactivity Triggers Electrophysiological Remodeling and Disrupts Excitation-Contraction Coupling in Heart

 

Wild Type (WT)

α2a/ α2c KO (ARDKO)

Body weight (g)

31.6 ± 2.4

30.4 ± 1.8 (n = 15 mice)

Heart/Body weight (mg/g)

7.4 ± 0.8

7.7 ± 0.4 (n = 15 mice)

Mean Arterial Pressure (mmHg)

124.0 ± 13.1

137.0 ± 12.1* (n = 15 mice)

Heart Rate (bpm)

540.4 ± 90.7

718.5 ± 23.6* (n = 15 mice)

Cell capacitance (pF)

189.8 ± 35.6 (n = 80 cells)

 214.8 ± 56.0* (n = 131 cells)

  1. *P < 0.05; compared to WT (Student’s t-test).
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