Figure 4

UGCG influences the lipid composition of ER/mitochondria fractions. (A) Total glucosylceramide, lactosylceramide, dihydro- (dh-) ceramide and ceramide levels of isolated ER/mitochondria fractions determined via LC-MS/MS. Data are presented as a mean of n = 6 ± SEM. (B) Levels of specific sphingolipids species following UGCG OE. Data are presented as a mean of n = 6 ± SEM. (C) Golgi phosphoprotein 3 (GOLPH3) mRNA level related to RPL37A determined by qRT-PCR. Data are presented as a mean of n = 5 ± SEM. *p ≤ 0.05, ***p ≤ 0.001.