Table 1 Characteristics HBV patients segregated according to clinical presentation.

From: Clinical significance of combined circulating TERT promoter mutations and miR-122 expression for screening HBV-related hepatocellular carcinoma

Characteristics

CHB (n = 98)

LC (n = 55)

HCC (n = 96)

P value

Age (years)

42 [21–85]

57 [27–79]

55 [23–92]

<0.05β

Male (%)

81

78

91

NSα

AST (IU/L)

96 [35–293]

69 [50–134]

69 [48–123]

NSβ

ALT (IU/L)

117 [36–453]

46 [29–85]

44 [30–84]

<0.0001β

Total bilirubin (mg/dl)

16 [12–61]

31 [22–58]

15 [11–20]

<0.0001β

Direct bilirubin (mg/dl)

5 [3–50]

15 [8–33]

4 [3–6]

<0.0001β

Albumin (g/L)

41 [38–43]

32 [28–38]

39 [35–42]

<0.0001β

Prothrombin (% of standard)

95 [81–108]

65 [53–79]

95 [85–106]

<0.0014β

WBC (x103/ml)

7.0 [5.6–8.6]

5.0 [4.3–6.7]

7.0 [5.7–8.7]

<0.0001β

RBC (x106/ml)

5.0 [4.6–5.3)

4.0 [3.4–4.2]

5.0 [4.3–5.2)

<0.0001β

PLT (x103/ml)

191 [153–237]

88 [64–113]

194 [142–238]

<0.0001β

HBV-DNA - log10(copies/ml)

6.0 [4.4–8.0]

5.2 [3.9–7.8]

5.0 [4.2–6.6]

NS β

AFP (IU/L)

2.0 [1.5–9.3]

11.0 [4.0–25.8]

126.0 [12.9–315.2]

<0.0001β

  1. CHB, chronic hepatitis B; LC, liver cirrhosis; HCC, hepatocellular carcinoma; RBC, red blood cells; WBC, white blood cells; PLT, platelets. AST and ALT, aspartate and alanine amino transferase; AFP, alpha-fetoprotein; IU, international unit; NR, normal range. Values given are medians with 25–75% percentiles. P values were calculated by chi-squared (α) or Kruskal-Wallis test (β).