Table 3 Neurological diseases and functions significantly associated with DEGs in the hippocampus of rats prenatally exposed to BPA.
Categories | P-value | # DEGs |
|---|---|---|
Both Sexes | ||
Neurological Diseases | ||
Autosomal recessive neurological disorder | 6.75E-13 | 267 |
Cognitive impairment | 1.65E-10 | 270 |
Motor dysfunction or movement disorder | 3.14E-10 | 429 |
Progressive neurological disorder | 2.45E-08 | 373 |
Dementia | 5.84E-06 | 228 |
Nervous System Development and Functions | ||
Development of neurons | 9.84E-09 | 316 |
Neuritogenesis | 1.71E-07 | 240 |
Morphology of cerebellar cortex cells | 2.84E-06 | 32 |
Synaptic transmission | 4.23E-06 | 130 |
Morphology of Purkinje cells | 4.58E-06 | 31 |
Male | ||
Neurological Diseases | ||
Cognitive impairment | 1.76E-23 | 158 |
Mental retardation | 2.10E-17 | 104 |
Movement disorders | 1.14E-15 | 204 |
Alzheimer disease | 1.97E-06 | 94 |
Tauopathy | 5.91E-06 | 95 |
Nervous System Development and Functions | ||
Development of neurons | 5.42E-27 | 192 |
Neuritogenesis | 7.83E-25 | 154 |
Proliferation of neuronal cells | 9.97E-13 | 111 |
Synaptic transmission | 1.16E-09 | 34 |
Memory | 3.95E-09 | 59 |
Female | ||
Neurological Diseases | ||
Cognitive impairment | 3.81E-23 | 226 |
Movement disorders | 1.44E-22 | 334 |
Mental retardation | 1.93E-13 | 137 |
Tauopathy | 1.18E-12 | 174 |
Alzheimer disease | 3.85E-12 | 167 |
Nervous System Development and Functions | ||
Development of neurons | 6.39E-40 | 310 |
Neuritogenesis | 6.61E-37 | 248 |
Proliferation of neuronal cells | 8.96E-25 | 197 |
Synaptic transmission | 7.6E-12 | 108 |
Memory | 2.43E-11 | 91 |
