Figure 3

Pattern of PICU antibiotic utilization in the pre- and post-implementation period. Use of WHO “Watch group” antibiotics meropenem and vancomycin was halfed (meropenem by 49%, vancomycin by 56%), and use of trimethoprime-sulfamethoxazole decreased significantly during the post-implementation period (p = 0.05). As intended by the antibiotic stewardship team, a sharp increase in ampicillin/sulbactam utilization was observed in the post-implementation period. Mann-Whitney-U-Test was used for comparison of DoT/1000 PD for each antibiotic per PICU stay; p < 0.05 was considered statistically significant.