Figure 1 | Scientific Reports

Figure 1

From: Genetic dissection of Rift Valley fever pathogenesis: Rvfs2 locus on mouse chromosome 11 enables survival to early-onset hepatitis

Figure 1

Representation of the MBT-derived Rvfs2 region in the congenic C.MBT-Rvfs2 strain and its effect on mouse survival. (A) Haplotype structure of the congenic segment of Chr 11 in C.MBT-Rvfs2 strain. The MBT-derived segment is depicted in white on the BALB/cByJ Chr 11 background (black). Regions of unknown genotype are depicted in grey. Markers are SNPs from the GigaMUGA array (see Table S2 from37) and position are given in bp from mouse Genome Build 38 (corrected from19). (B) Survival curves of C.MBT-Rvfs2 and BALB male mice infected with 100 PFU IP (Mantel-Cox’s Logrank test; p < 0.0001).

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