Figure 8 | Scientific Reports

Figure 8

From: Genetic dissection of Rift Valley fever pathogenesis: Rvfs2 locus on mouse chromosome 11 enables survival to early-onset hepatitis

Figure 8

Survival curves of chimeric mice generated by reciprocal transplantation of bone marrow cells. Sub-lethally irradiated C.MBT-Rvfs2 (Rvfs2, red lines) or BALB (black lines) recipient mice received ~3 × 106 bone marrow cells from either C.MBT-Rvfs2 (dashed lines) or BALB (solid lines) donor mice on the same day as irradiation. The recipient mice were infected intraperitoneally with 102 PFU RVFV six weeks later. Asterisks refer to the comparison between each group and the BALB → BALB control group (Mandel-Cox’s Logrank test; **p < 0.01, ***p < 0.001).

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