Table 3 Diagnostic performance variables of different ultrasound, clinical and laboratory parameters to predict acute kidney injury in bitches affected by sepsis/pyometra.

From: Clinical and ultrasound variables for early diagnosis of septic acute kidney injury in bitches with pyometra

Parameter

Cutoff point

Sensibility%

Specificity%

Accuracy%

Likelihood ratio

DiagAUC%

B-Mode

RLeng/AorRatio

>5.93

80

91.67

84.38

9.6

84.79

Doppler Ultrasonography

Pulsatility index

>1.53

70

91.67

81.25

8.4

87.90

TaMin (cm/s)

<21.50

75

91.67

84.38

9.0

87.08

TaMax (cm/s)

<45.70

80

83.30

81.25

4.8

87.80

Resistivity index

>0.71

70

83.30

75.00

4.2

80.42

RBF (ml/min/g rim)

<1.45

70

66.70

68.75

2.1

76.30

CEUS

CortPeak (%)

<69.00

70

98.00

81.25

8.4

75.00

Physical Exam

HR (bpm)

>123

70

75.00

75.00

2.8

82.30

Hemogram

Haematocrit (%)

<45

75

91.67

81.25

9.0

87.08

Haemoglobin (g/dL)

<16

73

83.33

81.25

4.5

83.13

Erythrocytes (x106/uL)

<6.64

70

76.00

75.00

2.8

79.83

Leukocytes (x103/uL)

>12.53

75

91.67

81.25

9.0

77.50

Biochemical

Albumin (g/dL)

<2.94

85

91.67

87.50

10.2

90.42

Globulins (g/dL)

>4.90

75

83.30

81.25

4.5

87.71

Urinalysis

UP/CR

>0.15

90

91.67

90.63

10.8

95.42

Haemogasometry

CaHCO3 (mmol/L)

<18.6

80

83.30

81.25

4.8

79.20

  1. UP/CR: urinary protein/creatinine ratio, CaHCO3: arterial bicarbonate concentration, RLeng/AorRatio: Renal length/aorta diameter ratio, TaMin: time-averaged minimum velocity, TaMax: time-averaged maximum velocity, RBF: Renal blood flow, CortPeak: Cortical peak contrast enhancement, DiagAUC: Area under the curve of receiving operating characteristic.