Figure 6
From: The impact of capsaicinoids on APP processing in Alzheimer’s disease in SH-SY5Y cells
Effect of capsaicinoids on Aβ degradation and aggregation. (a) Aβ degradation was examined in capsaicinoid treated murine neuroblastoma cells (N2a) by WB (n ≥ 9). (b) Influence of capsaicin on degradation of Aβ in N2a IDE knock-down cells (n = 9). (c) IDE activity assay in N2a cells after treatment with natural compound (n = 6). (d) THT-based Aβ aggregation assay (n = 9). Error bars represent the standard error of the mean. Asterisks show the statistical significance calculated by unpaired Student’s t test or ANOVA (*p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001).
