Table 4 Results of IPA downsream effects analysis for muscle atrophy genes in arctic ground squrrels at torpor entry as compared to summer active animals.
Genes in dataset | Prediction (based on expr change direction) | Expr Fold Change (this study) | Findings (reported in references) | Reference |
|---|---|---|---|---|
PPARGC1B | Decreased | 2.877 | Decreases | |
GADD45A | Increased | 2.667 | Increases | |
MET | Affected | 2.582 | Affects | |
MAMSTR | Decreased | 2.380 | Decreases | |
NFKBIA* | Decreased | −2.849 | Increases | |
FOXO3* | Decreased | −3.022 | Increases | |
GDF11 | Affected | −3.148 | Affects | |
CBLB | Decreased | −3.152 | Increases | |
FBXO32 | Decreased | −3.278 | Increases | |
DHTKD1 | Affected | −3.672 | Affects | NCBI, CLINVAR |
ATF3* | Affected | −3.988 | Affects | |
HSPB1* | Affected | −4.284 | Affects | |
FOXO1* | Decreased | −4.876 | Increases | |
TRIM63* | Decreased | −5.283 | Increases | |
CFLAR* | Affected | −5.747 | Affects |
