Figure 1

Evaluation of colonic hypersensitivity after infection with Blastocystis ST4. (a) Representative colonic response to colorectal distension (CRD) in infected (n = 12) and control (n = 6) rats at D31. (b) Area under the curve (AUC) of colonic response calculated by the trapeze method between 20 mmHg and 80 mmHg. (c) Correlation between relative abundance of Blastocystis and AUC of colonic response. Statistical analysis: a, Two-way ANOVA test followed by a Sidak post-hoc test; b, t-test; c, Spearman-test; *p < 0.05 **p < 0.01; three independent experiments were performed.