Table 6 Linear regression Models for metabolic factors in unaffected carriers. B(95%CI) and p values are presented for measures found significant in the model.

From: Metabolic syndrome does not influence the phenotype of LRRK2 and GBA related Parkinson’s disease

 

Number of metabolic factors

Prediabetes

Hypertension

Hypertriglyceridemia

Low HDL

Obesity

Model

F = 7.137; p < 0.001

F = 5.857; p < 0.0001

F = 0.481; p < 0.001

F = 7.030; p < 0.0001

F = 0.619; p = 0.781

F = 1.148; p = 0.329

Genotype

      

Sex

−0.459(−0.745–0.173); 0.002

−0.095(−0.194–0.003); 0.058

−0.171(−0.279–0.064); 0.002

−0.140(−0.248–0.032); 0.002

  

Age

0.048(0.033–0.063); 0.0001

0.015(0.010–0.020); 0.0001

0.014(0.008–0.019); 0.0001

0.016(0.011–0.022); 0.0001

  

Probability

      

RBDQ

      

UPDRS-III

 

−0.042(−0.077–0.007); 0.018

    

MOCA

 

−0.017(−0.035–0.001); 0.061

    

UPSIT

      

NMSQ

      
  1. RBDQ- REM sleep Behavior Disorder Questionnaire, UPDRS- Unified Parkinson’s Disease Rating Scale part III, MoCA- Montreal Cognitive Assessment, UPSIT- University of Pennsylvania Smell Identification Test, NMSQ- Non-Motor Symptoms questionnaire.