Figure 4
From: WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations
Functional significance of differentially expressed genes. (A) Venn diagram summarizing the extent to which differentially expressed genes from comparisons made in Fig. 3C overlap. (B) Top 10 Disease Gene Net enrichment results sorted by multiple test corrected p-value for the 312 genes upregulated in proximal and distal EpCAM+/ALDH+ cell populations compared to their EpCAM+/ALDH− counterparts. (C) Top 10 GO Biological Process enrichment results sorted by hits/background gene for the same 312 genes as Fig. 4B. (D) GSEA results for Hallmark Wnt/β-Catenin signaling. (E) Boxplots displaying β-Catenin signaling in each of the four cell populations. (F) Boxplots plots displaying TCF7 expression in each of the four cell populations. (G) Log2(Fold Change) for cell-cell signaling by Wnt genes between proximal and distal EpCAM+/ALDH+ cell populations.
