Figure 3

AO-IRAF signal variability in the fovea between healthy volunteers with normal vision. When comparing these images, there is a lot of variation in the signal. Some of the participants (e.g. 301) show a relatively clear cell mosaic, whereas others (e.g. 302 and 315) show pattered microstructures but lack the expected RPE cell mosaic. A strong AO-IRAF signal is seen with participant 039 but it does not manifest as the expected RPE mosaic but rather shows an intriguing microstructure with several hyper-reflective spots, on the order of the size of cones, that corresponded to positions where cones were clearly visible in the confocal photoreceptor image.