Table 1 Baseline characteristics.

From: Early-onset atrial fibrillation patients show reduced left ventricular ejection fraction and increased atrial fibrosis

 

AF with TTNtv (n = 17)

AF without TTNtv (n = 17)

Controls (n = 17)

P-value

P-value

Gender, male, n (%)

14 (82)

14 (82)

14 (82)

1.0

1.0

Age of AF onset, years (median [IQR])

25 (22–29)

25 (22–29)

 

Age at study time (median [IQR])

42 (39–45)

42 (40–45)

42 (37–44)

0.9

0.9

Height, cm (mean [SD]

183 (8)

185 (9)

180 (8)

0.3

0.4

BMI, kg/m2 (mean [SD])

26 (4)

27 (4)

26 (3)

0.8

0.6

Smoking, current or previously, n (%)

6 (35)

7 (41)

5 (29)

0.7

0.5

Alcohol consumption per week (mean [SD])

6 (7)

4 (3)

6 (6)

0.8

0.2

Hypertension, n (%)

3 (18)

1 (6)

2 (12)

0.6

0.2

Diabetes, n (%)

0 (0)

1 (6)

0 (0)

0.3

Heart failure, n (%)

0 (0)

1 (6)

0 (0)

0.3

Myocardial infarction, n (%)

0 (0)

0 (0)

0 (0)

Type of AF, n (%)

     

   Paroxysmal

11 (65)

14 (82)

 

   Persistent

6 (35)

2 (12)

 

   Permanent

0 (0)

1 (6)

 

Family history of AF, self-reported, n (%)

9 (53)

5 (29)

 

Previously ablated, n (%)

8 (47)

3 (18)

 

Physical exercise level, self-reported, n (%)

   

0.6

0.7

   None

1 (6)

0 (0)

1 (6)

  

   Mild

5 (29)

8 (47)

9 (53)

  

   Moderate

9 (53)

7 (41)

6 (35)

  

   Strenuous

1 (6)

2 (12)

1 (6)

  
  1. AF; atrial fibrillation, BMI; body mass index, IQR; interquartile range, NA; not available, SD; standard deviation, TTNtv; titin-truncating variant. Comparisons between AF patients with TTNtv and controls. Comparisons between AF patients without TTNtv and controls.