Table 1 Demographic and clinical characteristics of depressive patients.

From: Sex differences in the genetic architecture of depression

Variables

Females

(N = 707)

Males

(N = 293)

Ā 

P-value*

Socio-demographic characteristics

Age, mean(SD) years

57.2 (13.8)

55.9 (16.3)

t =ā€‰āˆ’1.18

0.237

Education, mean(SD) years

8.3 (4.8)

11.0 (4.3)

t =ā€‰āˆ’8.71

3.13 E-17

Marital status, n(%), married

492 (69.6)

209 (71.3)

χ2 = 0.22

0.637

Unemployment status, n(%)

171 (24.2)

101 (34.5)

χ2 = 10.55

0.001

Clinical characteristics

Diagnosis, n(%)

Ā Ā Ā Ā 

Ā Ā Ā Major depressive disorder

614 (86.8)

241 (82.3)

χ2 = 3.16

0.075

Ā Ā Ā Other depressive disorder

93 (13.2)

52 (17.7)

Ā Ā 

Episode of depression

Ā Ā Ā Recurrent depression (yes), n(%)

382 (54.0)

128 (43.7)

χ2 = 8.46

0.003

Ā Ā Ā Number of depression episode

1.9 (4.2)

1.6 (4.2)

t = 1.12

0.263

Ā Ā Ā Age at onset, mean(SD) years

51.6 (15.8)

52.9 (17.7)

t =ā€‰āˆ’1.12

0.264

Ā Ā Ā Duration of illness, mean(SD) day

284.0 (658.3)

307.5 (686.8)

t =ā€‰āˆ’0.50

0.618

Ā Ā Ā Family history of depression (yes),Ā  n(%)

116 (16.4)

34 (11.6)

χ2 = 3.38

0.066

Ā Ā Ā History of suicide attempt (yes), n(%)

55(7.8)

31(10.6)

χ2 = 1.73

0.189

Assessment scales, mean(SD) scores

Ā Ā Ā Hamilton Depression Rating Scale

20.9 (4.3)

20.2 (4.1)

t = 2.61

0.009

Ā Ā Ā Anxiety-subscale of Hospital Anxiety and Depression Scale

11.7 (4.0)

11.9 (4.0)

t =ā€‰āˆ’0.46

0.646

Ā  Ā Suicide item of Brief Psychiatric

Rating scale

Ā Ā Ā Ā  Ā Mild or less(1–3), n(%)

468 (66.2)

199 (67.9)

χ2 = 0.20

0.651

Ā Ā Ā Ā  Ā Moderate to extreme severe(4–7), n(%)

239(33.8)

94(32.1)

Ā Ā 

Features of depression, n(%)

Ā Ā Ā atypical feature (yes)

51 (7.2)

17 (5.8)

χ2 = 0.45

0.504

Ā Ā Ā melancholic feature (yes)

97 (13.7)

45 (15.4)

χ2 = 0.33

0.565

Ā Ā Ā psychotic feature (yes)

44 (6.2)

12 (4.1)

χ2 = 1.39

0.238

  1. *t-test, χ2 test, or Fisher’s exact tests, as appropriate.
  2. Values in bold type show broader significance cut-off (P < 0.1).