Table 1 Demographic and clinical characteristics of depressive patients.
From: Sex differences in the genetic architecture of depression
Variables | Females (Nā=ā707) | Males (Nā=ā293) | Ā | P-value* |
---|---|---|---|---|
Socio-demographic characteristics | ||||
Age, mean(SD) years | 57.2 (13.8) | 55.9 (16.3) | tā=āā1.18 | 0.237 |
Education, mean(SD) years | 8.3 (4.8) | 11.0 (4.3) | tā=āā8.71 | 3.13 E-17 |
Marital status, n(%), married | 492 (69.6) | 209 (71.3) | Ļ2ā=ā0.22 | 0.637 |
Unemployment status, n(%) | 171 (24.2) | 101 (34.5) | Ļ2ā=ā10.55 | 0.001 |
Clinical characteristics | ||||
Diagnosis, n(%) | Ā | Ā | Ā | Ā |
Ā Ā Ā Major depressive disorder | 614 (86.8) | 241 (82.3) | Ļ2ā=ā3.16 | 0.075 |
Ā Ā Ā Other depressive disorder | 93 (13.2) | 52 (17.7) | Ā | Ā |
Episode of depression | ||||
Ā Ā Ā Recurrent depression (yes), n(%) | 382 (54.0) | 128 (43.7) | Ļ2ā=ā8.46 | 0.003 |
Ā Ā Ā Number of depression episode | 1.9 (4.2) | 1.6 (4.2) | tā=ā1.12 | 0.263 |
Ā Ā Ā Age at onset, mean(SD) years | 51.6 (15.8) | 52.9 (17.7) | tā=āā1.12 | 0.264 |
Ā Ā Ā Duration of illness, mean(SD) day | 284.0 (658.3) | 307.5 (686.8) | tā=āā0.50 | 0.618 |
Ā Ā Ā Family history of depression (yes),Ā n(%) | 116 (16.4) | 34 (11.6) | Ļ2ā=ā3.38 | 0.066 |
Ā Ā Ā History of suicide attempt (yes), n(%) | 55(7.8) | 31(10.6) | Ļ2ā=ā1.73 | 0.189 |
Assessment scales, mean(SD) scores | ||||
Ā Ā Ā Hamilton Depression Rating Scale | 20.9 (4.3) | 20.2 (4.1) | tā=ā2.61 | 0.009 |
Ā Ā Ā Anxiety-subscale of Hospital Anxiety and Depression Scale | 11.7 (4.0) | 11.9 (4.0) | tā=āā0.46 | 0.646 |
Ā Ā Suicide item of Brief Psychiatric Rating scale | ||||
Ā Ā Ā Ā Ā Mild or less(1ā3), n(%) | 468 (66.2) | 199 (67.9) | Ļ2ā=ā0.20 | 0.651 |
Ā Ā Ā Ā Ā Moderate to extreme severe(4ā7), n(%) | 239(33.8) | 94(32.1) | Ā | Ā |
Features of depression, n(%) | ||||
Ā Ā Ā atypical feature (yes) | 51 (7.2) | 17 (5.8) | Ļ2ā=ā0.45 | 0.504 |
Ā Ā Ā melancholic feature (yes) | 97 (13.7) | 45 (15.4) | Ļ2ā=ā0.33 | 0.565 |
Ā Ā Ā psychotic feature (yes) | 44 (6.2) | 12 (4.1) | Ļ2ā=ā1.39 | 0.238 |