Figure 1

GWAS results and genetic correlations of broad sense self-harm thoughts and behaviours. Miami plot (left panel) depicts the genome-wide association results for the phenotypes studied. The x-axis represents the genomic position, while the y axis represents the significance of the association between each SNP and the phenotype; the top panel represents significance as –log10 (pvalue), while the bottom panel uses log10 (pvalue), in both cases, the farther from the x axis (middle) line, the more significant the association between the phenotype and the variant. On the right side, a heat map depicts the genetic correlations (rg) between published trait GWAS and our GWAS for self-harm ideation or self-harm behaviour. Only traits with a Benjamini-Hochberg fdr <0.01 for at least one phenotype and generated using studies independent from the UK-Biobank are depicted here (All the results, including UK-B traits, are available in Supplementary Data 1).