Figure 4 | Scientific Reports

Figure 4

From: Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy

Figure 4

GDF-15 decrease was accompanied by improvement of several clinical outcome measures in treated patients. Development of selected functional tests for patients in group 1: 6MWT (A), HMFS (B), HMFSE (C), and % FVC (D) and for patients in group 2: 6MWT (E), NSAA (F), and % FVC (G) during treatment with deoxynucleosides. Correlation between basal levels of GDF-15 and FGF-21 in serum for group 1 (black) and group 2 (red) patients together (H).

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