Figure 4
From: Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression

Mitochondrial fractal dimension correlated with structural and osteogenic markers. Fractal Dimension correlated with (a) ACTA2, (b) RHOA, (c) TGFβR1, (d) OPN, (e) OCN and (f) RUNX2 fold change for VIC cultures for days 1 through 28 under quiescent or osteogenic conditions on compliant or stiff substrates. Spearman’s Rank correlation coefficient is denoted as (Sp ρ).