Figure 5

Evaluation of cytokines/chemokines in culture supernatants of enriched MAIT cells and CD3⁺MR1⁻ cells. (A–G) Comparison of IL-6, IL-21, IL-18, MIF, CXCL12/SDF1, MIP1α/1β and IL-8 expression in the α-CD3/α-CD28 stimulated 24-hour culture supernatants of MAIT cells and CD3⁺MR1⁻ cells from naïve macaques. (H–M) Cytokines/chemokines in the culture supernatant of enriched MAIT cells from naïve, vaccinated, acute and chronically SIV-infected animals. Data of (A–M) were analyzed by Wilcoxon paired test. Horizontal and vertical bars denote mean and SEM. *p < 0.05, **p < 0.01.