Figure 7

MAIT cells drive B cells toward tissue resident memory B cell formation. (A,B) The fold change (calculated based on respective B cell alone data) of CD21−CD27− TLM B cells of naïve B cells stimulated with enriched (A) or sorted (B) MAIT cell supernatants in vitro. (C–J) Association or trend of association of the frequency of MAIT cells in blood or BAL 7 dpv with SIV Env-specific memory B cells in rectal mucosa 21 dpv. Data of (A,B) were analyzed by the Wilcoxon paired test. Horizontal and vertical bars denote mean and SEM. *p < 0.05. Data of (C–J) were analyzed by the Spearman correlation test.