Figure 4

Mammary gland involution markers analysed from mammary gland secretions for the 1.2 mg dose of inclusion bodies containing active (MMP-9 IBs) or inactive (mutMMP-9 IBs) matrix metalloproteinase-9 and control along 0, 1, 3, 6, and 9 d post-infusion. Non-transformed means and SEM (error bars) are represented while P-values were obtained from transformed data when necessary. Asterisks depict significant differences between treatments and the control group within time. (a) Bovine serum albumin (BSA); P < 0.0001. (b) Lactoferrin (LF); P < 0.0001. (c) Endogenous MMP-9 was analysed only for selected times: 0, 1, 3 and 9 d post-infusions; P < 0.05. (d) Na+/K+ ratio; P < 0.0001. For differences between different treatments within each time point, see Table S4 in the Supplementary Material.