Table 2 Univariate and multivariate Cox proportional hazards model based on the disease-free survival (DFS) in the 47 patients from TCGA-COAD.
From: A machine learning-based prognostic predictor for stage III colon cancer
Variable | Subtype | DFS/Univariate | DFS/Multivariate | ||||
|---|---|---|---|---|---|---|---|
P | HR | 95%CI | P | HR | 95%CI | ||
AI DFS status | High- vs. low-risk | 0.004 | 4.324 | 1.588–11.775 | 0.003 | 10.273 | 2.177–48.472 |
Age(y) | >50 vs. ≤50 | 0.887 | 0.921 | 0.297–2.861 | 0.967 | 1.044 | 0.140–7.770 |
Gender | Male vs. Female | 0.133 | 0.468 | 0.174–1.261 | 0.538 | 0.646 | 0.161–2.596 |
Tumor site | Left vs. Right colon | 0.152 | 0.428 | 0.134–1.368 | 0.740 | 0.789 | 0.195–3.199 |
Histologic type | Muc + Sig vs. Ade | 0.237 | 2.000 | 0.634–6.310 | 0.662 | 1.455 | 0.271–7.802 |
pT | T4 vs. T1–3 | 0.068 | 3.277 | 0.915–11.731 | 0.033 | 4.731 | 1.130–19.809 |
pN | N2 vs. N1 | 0.210 | 1.899 | 0.697–5.176 | 0.041 | 10.316 | 1.102–96.585 |
TNM stage | IIIC vs. IIIA + IIIB | 0.716 | 1.215 | 0.425–3.478 | 0.054 | 0.108 | 0.011–1.042 |
