Figure 6 | Scientific Reports

Figure 6

From: Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus

Figure 6

Human study - Mitochondrial respiratory capacity. Representative graph of mitochondrial respiratory capacity from an IR heart trabecula. Below mitochondrial respiratory capacity. GM, state 2 respiration with glutamate + malate (a); GM3, state 3 respiration with glutamate and malate (b); GMS3, state 3 respiration with glutamate, malate and succinate (c); 4o, state 4 respiration with oligomycin (d); FCCP, non-coupled state by FCCP (e); RCR with complex I-linked substrates (f). Data are mean ± SD. *P < 0.05 between indicated groups. P-values at the top indicate overall effect of diabetes and interventions by two-way ANOVA, respectively.

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