Figure 8 | Scientific Reports

Figure 8

From: Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus

Figure 8

Isolated rat heart study - Mitochondrial enzyme activity. Enzyme activity of citrate synthase (CS) and β-hydroxyacyl-CoA dehydrogenase (HAD) (a,b). Below protein content of individual electron transport chain complex I-V in non-diabetic (c) and diabetic (d) heart tissue. At the bottom Complex II activity in non-diabetic and diabetic tissue (e) and interstitial succinate concentrations (f). IR: Ischemia reperfusion, DiMAL: Dimethyl malonate. Data are the mean ± SD. *P < 0.05 between indicated groups. P-values at the top indicate overall effect of diabetes and interventions by two-way ANOVA, respectively.

Back to article page