Table 1 Cytokine analysis of MSCs and CIMVs-MSCs content.
Cytokine | MSCs (pg/ml) | CIMVs-MSCs (pg/ml) | Enrichment | P value |
|---|---|---|---|---|
IL-1β | 60.21 ± 18.30 | 244.82 ± 8.13 | 4.1 | < 0.003 |
IL-2 | 12.97 ± 1.51 | 25.97 ± 5.20 | 2.0 | < 0.04 |
IL-3 | 8.30 ± 0.11 | 22.02 ± 2.34 | 2.7 | < 0.007 |
IL-4 | 21.97 ± 3.19 | 40.10 ± 1.80 | 1.8 | < 0.01 |
IL-5 | 4.34 ± 1.16 | 18.79 ± 1.57 | 4.3 | < 0.005 |
IL-6 | 804.62 ± 127.98 | 3,084.32 ± 130.92 | 3.8 | 0.002 |
IL-9 | 202.76 ± 42.74 | 269.81 ± 18.80 | 1.3 | < 0.09 |
IL-10 | 10.26 ± 0.26 | 33.10 ± 3.54 | 3.2 | 0.006 |
IL-12(p40) | 3.20 ± 0.27 | 13.53 ± 0.24 | 4.2 | < 0.0003 |
IL-13 | 100.92 ± 17.87 | 326.62 ± 8.09 | 3.2 | < 0.002 |
IL-17 | 5.37 ± 0.13 | 12.46 ± 3.26 | 2.3 | < 0.046 |
CCL11 | 226.23 ± 34.20 | 562.91 ± 57.53 | 2.5 | < 0.01 |
G-CSF | 10.51 ± 0.48 | 60.43 ± 1.78 | 5.7 | < 0.0003 |
GM-CSF | 52.39 ± 5.28 | 130.50 ± 2.19 | 2.5 | < 0.001 |
CCL2 | 375.17 ± 37.56 | 2,764.96 ± 117.58 | 7.4 | < 0.0007 |
CCL3 | 10.79 ± 2.79 | 50.17 ± 5.43 | 4.6 | < 0.006 |
CCL4 | 11.12 ± 0.04 | 33.06 ± 2.11 | 3.0 | < 0.0023 |
CCL5 | 5 ± 0.49 | 18.86 ± 1.57 | 3.8 | < 0.0035 |
TNF-α | 54.98 ± 12.95 | 314.19 ± 23.26 | 5.7 | < 0.003 |
