Figure 2 | Scientific Reports

Figure 2

From: Selective whole genome amplification of Plasmodium malariae DNA from clinical samples reveals insights into population structure

Figure 2

Correlation between parasite density and genome coverage. (a) Nine samples (amplified with SWGA approach) were used to assess the effect of parasite density (as measured by CT values obtained from qPCR) on the proportion of the genome covered by five or more reads. Each point demonstrates a single sample, with a lowess line of best fit. The dashed horizontal line represents a cut off of 50% of the genome covered by 5 or above, and the dashed vertical line indicates the suggested CT cut-off of 30. (b) The same plot is shown using parasitaemia as the measure of parasite density (percentage of RBCs parasitized). Parasitaemias range from 0.0004% to 0.2024%, and the vertical dashed line represents the suggested parasitaemia cut-off of 0.01%.

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