Figure 3 | Scientific Reports

Figure 3

From: Selective whole genome amplification of Plasmodium malariae DNA from clinical samples reveals insights into population structure

Figure 3

Defining and excluding subtelomeric regions, an example with chromosome 1. The average coverage (pink) and number of SNPs (blue) between all 18 samples for chromosome 1. The black dashed horizontal line demonstrates the previously chosen SNP limit per 5 kb window (as defined in S2 Fig.). Black dashed lines are placed at the suggested hypervariable region cut-off points, where clusters of windows demonstrating > 2.25 SNPs are seen. The midpoints of Pm-fam gene families are annotated; Pm-fam-l gene positions are denoted by a black plus, whilst Pm-fam-m gene positions are denoted with a grey circle. (S3 Fig. for all chromosomes, S3 Table for coordinates).

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