Table 1 Morphological parameters of dendritic structures. Morphometric features were compared between genotypes. n ≥ 30 neurons from 7 mice of each genotype. Data are mean ± SEM. **p < 0.01; ***p < 0.001. Two-tailed unpaired Student’s t-test.

From: An important role of PHRF1 in dendritic architecture and memory formation by modulating TGF-β signaling

 

Apical dendrites

Basilar dendrites

PHRF1fl/fl

PHRF1Δ/Δ

PHRF1fl/fl

PHRF1Δ/Δ

Bifurcation nodes

23.34 ± 9.24

16.06 ± 0.79***

17.97 ± 1.16

11 ± 0.64***

Terminal ends

24.29 ± 1.50

16.88 ± 0.83***

20.87 ± 1.16

13.61 ± 0.63***

Highest order

13.24 ± 0.52

11.27 ± 0.41**

6.74 ± 0.28

5.7 ± 0.24**

Dendritic length (μm)

1599.76 ± 75.41

1015.19 ± 50.36***

1144.55 ± 48.61

686.62 ± 32.80***

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