Table 1 Summary of interactions within clusters for GSE100833.

From: Novel candidate drugs in anti-tumor necrosis factor refractory Crohn’s diseases: in silico study for drug repositioning

 

The number of genes

The number of protein

Actual interactions

Expected interactions

p-value

Ratio

Cluster 1

158

145

443

102

< 0.001

4.343

Cluster 2

25

25

0

0

1.00

–

Cluster 3

35

31

19

2

< 0.001

9.5

Cluster 4

42

33

3

0

< 0.001

–

Up

193

176

508

136

< 0.001

3.735

Down

67

58

6

2

< 0.001

3

All_DE

260

234

557

178

< 0.001

3.129

  1. STRING interactions are shown for each cluster, up or down-regulated genes and all DEGs, how many genes (gene in cluster), how many proteins (protein in STRING), how many interactions (actual interaction), how many expected interactions (expected interaction), the ratio of actual interactions and expected interactions, together with the p value to get such a number of interactions by chance.
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