Figure 2 | Scientific Reports

Figure 2

From: The colonic mucosa-associated microbiome in SIV infection: shift towards Bacteroidetes coincides with mucosal CD4+ T cell depletion and enterocyte damage

Figure 2

Composition of the colonic mucosa-associated microbiome at the phylum level before and after SIV infection. (A) Stacked bar representing the relative abundance of the top four most abundant phyla within colon biopsies in six animals before they were infected with SIV. Lower abundant bacteria (Actinobacteria, < 0.2%; Fusobacteria, < 0.2%; and Verrucomicrobia, < 0.5% in each animal) and bacteria that were not identified as belonging to any known phylum (mean 11%, range 3.8—22.6%) were termed ‘Others’. (B) and (C), Relative abundance of the four major phyla (B) and the ratio of Firmicutes to Bacteroidetes (C) before and at different stages of SIV infection. Values correspond to the frequency within the total bacteria detected within each animal. Mucosal peak viral load was observed on day 7 (black symbols) or day 14 after infection (grey symbols). The chronic phase was analyzed on day 49 after infection. Horizontal lines indicate mean values + /− standard deviations. *P < 0.05. VL, Viral load.

Back to article page