Figure 1

Solar plot showing significant hits from mitochondrial association testing. Each dot represents a detected variant. The inner ring of the plot represents the mitochondrial genome and is coloured based on genomic region as summarised in the plot legend. The X-axis represents the mitochondrial base pair location. The Y-axis represents the significance level [− log10 (P-value)] in the Gene SMART population over multiple traits. The significance threshold was set at P < 0.05 and is represented by the circular blue line. The concentric white rings surrounding the genome represent the P-value thresholds − log10 (0.01) and − log10 (0.001) respectively.