Figure 11 | Scientific Reports

Figure 11

From: Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles

Figure 11

Anti-cancer efficacy of DOX-EDT-IONPs compared to the free DOX on an MDCK-MDR-GBM model in vitro. (a) DOX permeability across the MDCK-MDR1 monolayer with or without IONPs in the presence or absence of magnet and ADTC5 (b) cytotoxicity of each formulation on U251 cells after penetrating the monolayer. (c) DOX-IONPs permeability across the MDCK-MDR1 monolayer with or without magnet and ADTC5. *Indicates a significant difference at p < 0.05 with the other treated groups. Data is presented as mean ± S.D, and n = 3. IONPs and DOX-IONPs represent for EDT-IONPs and DOX-EDT-IONPs.

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