Figure 5

Time-course analysis. TA muscles were electroporated with 1 µg of pCIneo-DUX4 and 10 µg of pCMV-LacZ. Lesion area was evaluated 1-, 3- or 7-days after hIMEP in the injected area (β-gal+) on HEB stained cryosections of medial and proximal TA regions (color thresholding, ImageJ). Results are presented as boxplots, *p < 0.05 and **p < 0.01. One-way ANOVA on the ranks followed by Dunn’s post hoc test; n = 3 for each group. Scale 1 mm. The graph was generated using GraphPad Prism 6.01.