Table 3 Correlation analysis between levels of soluble Aβ oligomers and cognitive function.

From: Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer’s disease

 

Normal—mild

Normal—Moderate

Normal—Mild + Moderate

Self-standard ratio (a.u)

R = 0.5603

(***)

R = 0.3087

(***)

R = 0.5239

(***)

Aβ*56 level (a.u) (ratio of normal)

R = 0.6815

(***)

R = 0.6909

(***)

R = 0.5246

(***)

AβO level (a.u) (ratio of normal)

R = 0.6061

(***)

R = 0.4010

(***)

R = 0.5173

(***)

  1. Correlation analysis between the total levels of soluble Aβ species (Self-standard ratio, Aβ*56 and AβO) in nasal discharges and MMSE scores was conducted. Linear regression analyses of the total oligomeric soluble Aβ showed significant correlation with the MMSE score. We calculated the correlation between soluble Aβ oligomer levels and cognitive function with the line shows the regression line with 95% confidence interval. Statistical significances are denoted (***P < 0.001).