Table 1 Descriptive information of TCGA dataset.
From: Homologous repair deficiency score for identifying breast cancers with defective DNA damage response
Characteristics | Number of patients (%) |
|---|---|
Sex | |
Female | 970 (98.9) |
Male | 11 (1.1) |
TNM stage | |
I | 167 (17.0) |
II | 567 (57.8) |
III | 216 (22.0) |
IV | 21 (2.1) |
N/A | 10 (1.0) |
Estrogen receptor status | |
Positive | 718 (73.2) |
Indeterminate | 2 (0.2) |
Negative | 216 (22.0) |
N/A | 45 (4.6) |
PAM50 subtype | |
Luminal A | 443 (45.2) |
Luminal B | 179 (18.2) |
HER2 | 70 (7.1) |
Basal-like | 154 (15.7) |
Normal-like | 122 (12.4) |
N/A | 13 (1.3) |
Germline BRCA mutation | |
BRCA1 | 20 (2.0) |
BRCA2 | 30 (3.0) |
BRCA1 and BRCA2 | 1 (0.1) |
Signature | |
CpG | 316 (32.2) |
APOBEC | 161 (16.4) |
BRCA | 484 (49.3) |
MSI | 20 (2.0) |
