Table 1 Baseline clinico-radiological data, overall survival and progression-free survival of patients with and without WHO grade increase at first recurrence.

From: Histological transformation in recurrent WHO grade I meningiomas

 

WHO grade increase

No WHO grade increase

p

n = 13

%

n = 1,342

%

Age

55.5 ± 11.6

58 ± 13.2

0.44

Sex

8 F/5 M

957 F/382 M

0.53

Skull base tumor

5

38.5

653

48.7

0.58

Bone infiltration

1

7.7

248

18.5

0.48

Simpson grade after initial surgery

    

0.28

I

4

30.8

532

39.8

 

II

6

46.2

458

34.2

 

III

0

0

70

5.3

 

IV

3

23

272

20.4

 

V

0

0

5

0.3

 

Postop RT after 1st surgery

0

0

28

2.1

0.96

OS

11.1 ± 6.2

9.2 ± 5.6

0.29

RFS

5 ± 4.1

7.3 ± 5.4

0.03

  1. OS overall survival, Neuro. Worsening neurological worsening, Postop RT post-operative radiation therapy, PFS progression-free survival.