Table 1 Baseline clinico-radiological data, overall survival and progression-free survival of patients with and without WHO grade increase at first recurrence.
From: Histological transformation in recurrent WHO grade I meningiomas
WHO grade increase | No WHO grade increase | p | |||
|---|---|---|---|---|---|
n = 13 | % | n = 1,342 | % | ||
Age | 55.5 ± 11.6 | – | 58 ± 13.2 | – | 0.44 |
Sex | 8 F/5 M | – | 957 F/382 M | – | 0.53 |
Skull base tumor | 5 | 38.5 | 653 | 48.7 | 0.58 |
Bone infiltration | 1 | 7.7 | 248 | 18.5 | 0.48 |
Simpson grade after initial surgery | 0.28 | ||||
I | 4 | 30.8 | 532 | 39.8 | |
II | 6 | 46.2 | 458 | 34.2 | |
III | 0 | 0 | 70 | 5.3 | |
IV | 3 | 23 | 272 | 20.4 | |
V | 0 | 0 | 5 | 0.3 | |
Postop RT after 1st surgery | 0 | 0 | 28 | 2.1 | 0.96 |
OS | 11.1 ± 6.2 | – | 9.2 ± 5.6 | – | 0.29 |
RFS | 5 ± 4.1 | – | 7.3 ± 5.4 | – | 0.03 |