Table 2 Inter-researcher reproducibility of HRV parameters derived from short-term recordings.

From: Inter- and intra-researcher reproducibility of heart rate variability parameters in three human cohorts

 

Researcher 1

Mean ± stand. deviation

Researcher 2

Mean ± stand. deviation

Mean difference

 ± stand. deviation

95% limits of agreement

ICC (95% CI)

CV (%)

RMSE

Children with overweight/obesity (n = 107)

RMSSD (ms)

61.66 ± 33.22

59.76 ± 30.66

1.71 ± 8.20

− 14.38; 17.81

0.966 (0.950;0.977)

3.8

9.17

pNN50 (%)

30.45 ± 20.37

29.98 ± 19.75

0.31 ± 2.91

− 5.40; 6.02

0.989 (0.985;0.993)

3.9

3.13

SDNN (ms)

59.04 ± 25.98

57.74 ± 24.53

1.29 ± 6.48

− 11.41; 13.99

0.966 (0.951;0.977)

3.3

8.47

FFT_HF (ms2)

1898.07 ± 1937.11

1767.70 ± 1744.89

126.79 ± 736.13

− 1,316.02; 1569.60

0.919 (0.883;0.994)

15.9

752.02

AR_HF (ms2)

1855.29 ± 1852.42

1756.60 ± 1698.83

92.62 ± 641.94

− 1,165.58; 1,350.81

0.934 (0.905;0.955)

7.8

651.39

FFT_LF (ms2)

1688.39 ± 1599.80

1674.03 ± 1557.16

34.20 ± 456.80

− 861.13; 929.53

0.958 (0.939;0.971)

15.3

582.68

AR_LF (ms2)

1538.49 ± 1,348.11

1566.66 ± 1,371.32

− 22.02 ± 331.67

− 672.10; 628.05

0.971 (0.957;0.980)

8.4

392.76

FFT_LF/HF

1.27 ± 0.94

1.28 ± 0.82

0.00 ± 0.53

− 1.03; 1.03

0.823 (0.751;0.876)

14.9

0.58

AR_LF/HF

1.14 ± 0.71

1.18 ± 0.69

− 0.04 ± 0.32

− 0.66; 0.59

0.895 (0.850;0.927)

10.5

0.37

Young adults (n = 132)

RMSSD (ms)

58.75 ± 32.16

60.20 ± 31.49

− 1.45 ± 4.71

− 10.68; 7.78

0.988 (0.982;0.992)

3.3

4.91

pNN50 (%)

33.24 ± 22.25

34.07 ± 21.90

− 0.82 ± 3.69

− 8.06; 6.41

0.985 (0.979;0.990)

6.0

4.55

SDNN (ms)

52.20 ± 23.86

53.89 ± 23.95

− 1.69 ± 4.24

− 10.00; 6.62

0.982 (0.969;0.989)

3.6

3.77

FFT_HF (ms2)

1594.27 ± 1789.73

1,700.78 ± 1814.40

− 106.51 ± 420.69

− 931.07; 718.05

0.971 (0.958;0.980)

12.5

432.42

AR_HF (ms2)

1626.19 ± 1777.48

1675.50 ± 1717.53

− 49.31 ± 295.96

− 629.39; 530.76

0.985 (0.979;0.990)

8.0

298.93

FFT_LF (ms2)

1,235.20 ± 1,307.97

1,350.06 ± 1,493.56

− 144.86 ± 874.79

− 1751.04; 1521.32

0.822 (0.757;0.870)

17.2

839.51

AR_LF (ms2)

1,237.36 ± 1,330.89

1,349.15 ± 1,464.88

− 111.79 ± 410.93

− 917.22; 693.63

0.954 (0.933;0.968)

10.8

424.36

FFT_LF/HF

1.20 ± 1.21

1.15 ± 1.02

0.05 ± 0.64

− 1.21; 1.31

0.834 (0.773;0.879)

16.7

0.64

AR_LF/HF

1.14 ± 0.96

1.12 ± 0.87

0.02 ± 0.32

− 0.61; 0.65

0.939 (0.916;0.957)

10.5

0.32

Middle-aged adults (n = 73)

RMSSD (ms)

31.33 ± 19.54

32.43 ± 19.54

− 0.94 ± 4.74

− 10.23; 8.34

0.970 (0.952;0.981)

4.7

4.77

pNN50 (%)

12.80 ± 16.23

13.25 ± 16.22

− 0.30 ± 2.67

− 5.52; 4.93

0.987 (0.979;0.992)

8.9

2.66

SDNN (ms)

30.18 ± 13.95

31.36 ± 13.94

− 1.05 ± 5.22

− 11.28; 9.19

0.928 (0.888;0.955)

5.1

5.29

FFT_HF (ms2)

462.42 ± 607.67

492.49 ± 617.23

− 25.57 ± 200.10

− 417.75; 366.62

0.947 (0.916;0.966)

16.0

200.34

AR_HF (ms2)

473.05 ± 624.58

488.12 ± 585.05

− 10.66 ± 154.91

− 314.28; 292.96

0.968 (0.949;0.980)

9.7

154.19

FFT_LF (ms2)

469.06 ± 435.09

505.92 ± 463.28

− 25.86 ± 246.89

− 509.76; 458.05

0.850 (0.771;0.903)

21.1

246.53

AR_LF (ms2)

466.17 ± 442.23

505.27 ± 459.28

− 29.05 ± 200.98

− 422.97; 364.87

0.900 (0.846;0.936)

11.7

201.68

FFT_LF/HF

2.22 ± 3.29

2.03 ± 2.88

0.19 ± 2.39

− 4.50; 4.89

0.703 (0.564;0.803)

18.3

2.38

AR_LF/HF

1.98 ± 2.19

2.08 ± 2.79

− 0.13 ± 0.97

− 2.04; 1.78

0.925 (0.882;0.952)

12.8

0.98

  1. HRV heart rate variability, RMSSD the square root of the mean of the sum of the squares of differences between adjacent R–R intervals, pNN50 percentage (%) of the total pairs of R–R intervals that differ by more than 50 ms, SDNN standard deviation of all normal R–R intervals, FFT fast Fourier Transformation algorithm, HF high frequency (0.15–0.4 Hz) index of parasympathetic activity, LF low frequency (0.04–0.15 Hz) mix index of sympathetic and parasympathetic activity, AR autoregressive algorithm, ms milliseconds, CV coefficient of variation, ICC intraclass correlation coefficient, RMSE root mean square error.
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