Figure 6

The model characterization of cellular traction force for one representative untreated MCTS system is shown. X and Y deformation field images are determined based on non-rigid registration of observational microscopy imaging of fluorescent microbeads over time. Using the model-fit cellular density parameters and observational deformation field images in combination with our computational model, a cellular traction force parameter is estimated between each imaging time point. The figure reflects the cumulative cellular traction force overtime in both and X and Y displacement directions. Error maps show the model-data misfit for both X and Y deformation.