Table 2 Iloprost-induced changes in phosphoproteome and platelet functions.

From: Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS

  1. All 2,516 phosphopeptides of the iloprost phosphoproteome, identified in control platelets, were assigned to 22 platelet function classes, according to Uniprot. Indicated per class are the fractions of phosphopeptides identified as up- or downregulated by 2 or 10 nM iloprost, in platelets from ≥ 3 control subjects (C1–4). Note that cut-off levels were used per column to define downregulation or upregulation, as for Fig. 4. Indicated also are numbers (n) of altered phosphopeptides per function class.
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