Table 2 Patients: tumor volumes were estimated in triplicate in a total of 32 MRI scans with each of three different methods.

From: MRI based volumetric measurements of vestibular schwannomas in patients with neurofibromatosis type 2: comparison of three different software tools

Parameter

Osirix

ITK-SNAP

BrainLab

Patient 1

MRI #1

Mean estimated volume (ml)

3.77

4.52

3.51

 Standard deviation (ml)

0.09

0.13

0.02

 Coefficient of variation

0.02

0.03

0.01

MRI #2

 Mean estimated volume (ml)

3.96

4.40

3.63

 Standard deviation (ml)

0.02

0.06

0.02

 Coefficient of variation

0.00

0.01

0.01

MRI #3

 Mean estimated volume (ml)

3.97

4.34

3.71

 Standard deviation (ml)

0.04

0.12

0.13

 Coefficient of variation

0.01

0.03

0.03

MRI #4

 Mean estimated volume (ml)

4.07

4.42

4.00

 Standard deviation (ml)

0.04

0.07

0.13

 Coefficient of Variation

0.01

0.02

0.03

Patient 2

MRI #1

 Mean estimated volume (ml)

5.80

6.67

5.16

 Standard deviation (ml)

0.04

0.03

0.10

 Coefficient of variation

0.01

0.00

0.02

MRI #2

 Mean estimated volume (ml)

6.38

6.80

5.54

 Standard deviation (ml)

0.07

0.12

0.02

 Coefficient of variation

0.01

0.02

0.00

MRI #3

 Mean estimated volume (ml)

6.62

6.61

5.36

 Standard deviation (ml)

0.08

0.20

0.01

 Coefficient of Variation

0.01

0.03

0.00

MRI #4

 Mean estimated volume (ml)

6.46

6.61

6.46

 Standard deviation (ml)

0.23

0.07

0.06

 Coefficient of variation

0.04

0.01

0.01

Patient 3

MRI #1

 Mean estimated volume (ml)

3.09

3.50

3.17

 Standard deviation (ml)

0.07

0.13

0.04

Coefficient of variation

0.02

0.04

0.01

MRI #2

 Mean estimated volume (ml)

3.73

3.44

2.75

 Standard deviation (ml)

0.06

0.07

0.06

 Coefficient of variation

0.02

0.02

0.02

MRI #3

 Mean estimated volume (ml)

3.64

3.68

3.03

 Standard deviation (ml)

0.11

0.13

0.06

 Coefficient of variation

0.03

0.03

0.02

MRI #4

 Mean estimated volume (ml)

3.58

3.69

2.90

 Standard deviation (ml)

0.02

0.02

0.02

 Coefficient of variation

0.01

0.00

0.01

Patient 4

MRI #1

 Mean estimated volume (ml)

8.39

8.86

7.90

 Standard deviation (ml)

0.06

0.24

0.02

 Coefficient of variation

0.01

0.03

0.00

MRI #2

 Mean estimated volume (ml)

9.03

9.18

8.35

 Standard deviation (ml)

0.11

0.03

0.06

 Coefficient of variation

0.012

0.00

0.01

MRI #3

 Mean estimated volume (ml)

13.16

13.61

12.35

 Standard deviation (ml)

0.14

0.32

0.18

 Coefficient of variation

0.011

0.023

0.015

MRI #4

 Mean estimated volume (ml)

11.64

11.42

10.52

 Standard deviation (ml)

0.12

0.13

0.32

 Coefficient of variation

0.01

0.01

0.03

Patient 5

MRI #1

 Mean estimated volume (ml)

0.53

0.57

0.40

 Standard Deviation (ml)

0.00

0.02

0.01

 Coefficient of Variation

0.00

0.03

0.03

MRI #2

 Mean estimated volume (ml)

0.57

0.50

0.49

 Standard deviation (ml)

0.01

0.02

0.01

 Coefficient of variation

0.01

0.04

0.02

MRI #3

 Mean estimated volume (ml)

0.57

0.58

0.50

 Standard deviation (ml)

0.01

0.03

0.01

 Coefficient of variation

0.01

0.05

0.02

MRI #4

 Mean estimated volume (ml)

0.55

0.54

0.47

 Standard deviation (ml)

0.01

0.05

0.01

 Coefficient of variation

0.01

0.09

0.02

Patient 6

MRI #1

 Mean estimated volume (ml)

0.42

0.68

0.49

 Standard deviation (ml)

0.01

0.04

0.02

 Coefficient of variation

0.02

0.06

0.05

MRI #2

 Mean estimated volume (ml)

0.44

0.70

0.53

 Standard deviation (ml)

0.00

0.01

0.03

 Coefficient of variation

0.01

0.02

0.05

MRI #3

 Mean estimated volume (ml)

0.46

0.68

0.56

 Standard deviation (ml)

0.02

0.03

0.04

 Coefficient of variation

0.03

0.04

0.08

MRI #4

 Mean estimated volume (ml)

0.48

0.69

0.60

 Standard deviation (ml)

0.01

0.02

0.02

 Coefficient of variation

0.02

0.03

0.03

Patient 7

MRI #1

 Mean estimated volume (ml)

0.22

0.45

0.28

 Standard deviation (ml)

0.01

0.03

0.01

 Coefficient of variation

0.03

0.06

0.05

MRI #2

 Mean estimated volume (ml)

0.24

0.50

0.27

 Standard deviation (ml)

0.01

0.00

0.01

 Coefficient of variation

0.04

0.00

0.04

MRI #3

 Mean estimated volume (ml)

0.27

0.50

0.30

 Standard deviation (ml)

0.02

0.04

0.01

 Coefficient of Variation

0.09

0.07

0.01

MRI #4

 Mean estimated volume (ml)

0.28

0.49

0.32

 Standard deviation (ml)

0.01

0.02

0.00

 Coefficient of variation

0.02

0.04

0.02

Patient 8

MRI #1

 Mean estimated volume (mll)

0.14

0.31

0.22

 Standard deviation (ml)

0.00

0.01

0.02

 Coefficient of variation

0.03

0.04

0.08

MRI #2

 Mean estimated volume (ml)

0.13

0.30

0.27

 Standard deviation (ml)

0.01

0.01

0.02

 Coefficient of variation

0.09

0.03

0.08

MRI #3

 Mean estimated volume (ml)

0.13

0.33

0.27

 Standard deviation (ml)

0.01

0.01

0.02

 Coefficient of variation

0.04

0.02

0.06

MRI #4

 Mean estimated volume (ml)

0.10

0.34

0.28

 Standard deviation (ml)

0.01

0.02

0.02

 Coefficient of variation

0.08

0.06

0.08

  1. We calculated the means, standard deviations (SD) and coefficients of variation (CV) of the three volume estimates at each time point for each patient using each method.