Figure 4

Schematic diagram of the path analyses for effect of A/T/N imaging biomarkers on odor identification ability. Path analysis for odor identification ability was performed using ¹⁸F-florbetaben, ¹⁸F-flortaucipir SUVR and cortical volume as predictors and the total cognition score as a mediator. In the upper part, total effects (direct effect + indirect effect) of the A/T/N imaging biomarkers on odor identification are shown. In (c, d), the lower side of the triangle represents the direct effects of the cortical volume on odor identification ability. Indirect effects of the A/T/N imaging biomarkers on odor identification ability are obtained by multiplying two β-coefficients between A/T/N imaging biomarkers and cognition, and between cognition and odor identification ability. Only significant β-coefficients are shown. **P < 0.001, *P < 0.05.